Normal Endometrium vs Endometrial Hyperplasia



Types of Endometrial Hyperplasia



Why clinically important ?


  1.  Because of progression towards malignancy 

2.  Because of abnormal uterine bleeding

Pathologically glands of simple type are large, lined by columnar epithelium 

but in complex type, small & over loaded lined by squamous epithelium

Typia vs Atypia

Pic says Atypia cells are

  • Irregular ,
  • Loss of polarity,
  • Hyperchromatic,
  • Nucleo Cytoplasmic ratio altered


but without atypia treatment is medically

for premenopusal

  • postmenopausally there is no treat for simple type
  • complex type- medroxyprogesteron acetate
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