ENDOMETRIAL HYPERPLASIA

Normal Endometrium vs Endometrial Hyperplasia

 


 

Types of Endometrial Hyperplasia

 

 


Why clinically important ?

 

  1.  Because of progression towards malignancy 

2.  Because of abnormal uterine bleeding


Pathologically glands of simple type are large, lined by columnar epithelium 

but in complex type, small & over loaded lined by squamous epithelium


Typia vs Atypia

Pic says Atypia cells are

  • Irregular ,
  • Loss of polarity,
  • Hyperchromatic,
  • Nucleo Cytoplasmic ratio altered

Treatment

but without atypia treatment is medically

for premenopusal

  • postmenopausally there is no treat for simple type
  • complex type- medroxyprogesteron acetate
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